-- DavidKeating - 20 Oct 2008

Module 32 - S-Cone

The next draft will be compiled by (Jägle + Holder)

1. Scope

For light adapted conditions

2. Identification

2.1. Number

32

2.2. Version number

1.0

2.3. Date of approval

3. Protocol use(s)

Assessment S-Cone responses.

4. Patient population

Genetic rod-cone degenerations

Toxicity studies

5. Technical issues

4.1. Equipment and facilities

No specific definition, see ISCEV Standard (2008 update) and Protocols general aspects.

4.2. Staff expertise and responsibilities

No specific definition, see ISCEV Standard (2008 update) and Protocols general aspects.

4.3. Procedure

No specific definition, see ISCEV Standard (2008 update) and Protocols general aspects.

4.4. Patient Information

No specific definition, see ISCEV Standard (2008 update) and Protocols general aspects.

6. Response evaluation (with example)

Amplitude and latency of responses.

7. Reporting and storage

Curves and amplitudes;

8. Calibration

No specific definition, see ISCEV Standard (2008 update) and Protocols general aspects. 9. Protocol Specifications

Description

S Cone

Averages per step

2

Adaptation time

0

Acquisition

Sample frequency

1000 (Hz)

Sweep pre-trigger time

20 (ms)

Sweep post-trigger time

600 (ms)

Sweeps per result

30

Interstimulus interval

1000(ms)

Drift removal

On

Manual rejection of sweeps

Off

DC off-set removal

On: 20 (ms)

Stimulus

Pulse frequency

Pulse duration (d)

Stimulus luminance

1st flash 1000 ph cd.s/m² RED (d=4ms)

100 ms delay

2nd flash 1000 ph cd.s/m² RED (d=4 ms)

100 ms delay

3rd flash 6 ph cd.s/m²

BLUE (100 ms)

Stimulus color

RED and BLUE

Background luminance

90 cd/m2

Background color

Amber

Channels (1 and 2)

Filter low frequency cutoff

0.3 (Hz)

Filter high frequencycutoff

300 (Hz)

Y-axis scaling

20 (uV)

10. Relevant References

-- TWikiAdminUser - 11 Feb 2009

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Topic revision: r6 - 12 Feb 2009 - 19:00:47 - TWikiAdminUser
 
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